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The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway

The INhibitor of Growth (ING) proteins act as type II tumor suppressors and epigenetic regulators, being stoichiometric members of histone acetyltransferase and histone deacetylase complexes. Expression of the alternatively spliced ING1a tumor suppressor increases >10-fold during replicative sene...

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Detalles Bibliográficos
Autores principales:	Rajarajacholan, Uma Karthika, Thalappilly, Subhash, Riabowol, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589274/ https://www.ncbi.nlm.nih.gov/pubmed/23472054 http://dx.doi.org/10.1371/journal.pbio.1001502

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