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Pitfalls in Experimental Designs for Characterizing the Transcriptional, Methylational and Copy Number Changes of Oncogenes and Tumor Suppressor Genes

BACKGROUND: It is a common practice that researchers collect a set of samples without discriminating the mutants and their wild-type counterparts to characterize the transcriptional, methylational and/or copy number changes of pre-defined candidate oncogenes or tumor suppressor genes (TSGs), althoug...

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Detalles Bibliográficos
Autores principales: Zhang, Yuannv, Xia, Jiguang, Zhang, Yujing, Qin, Yao, Yang, Da, Qi, Lishuang, Zhao, Wenyuan, Wang, Chenguang, Guo, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589351/
https://www.ncbi.nlm.nih.gov/pubmed/23472150
http://dx.doi.org/10.1371/journal.pone.0058163