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Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands
The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of the research into trafficking of the receptor after...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589378/ https://www.ncbi.nlm.nih.gov/pubmed/23472148 http://dx.doi.org/10.1371/journal.pone.0058148 |