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Tom70 Is Essential for PINK1 Import into Mitochondria
PTEN induced kinase 1 (PINK1) is a serine/threonine kinase in the outer membrane of mitochondria (OMM), and known as a responsible gene of Parkinson's disease (PD). The precursor of PINK1 is synthesized in the cytosol and then imported into the mitochondria via the translocase of the OMM (TOM)...
Autores principales: | Kato, Hiroki, Lu, Qiping, Rapaport, Doron, Kozjak-Pavlovic, Vera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589387/ https://www.ncbi.nlm.nih.gov/pubmed/23472196 http://dx.doi.org/10.1371/journal.pone.0058435 |
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