Primary Microcephaly Gene MCPH1 Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma

Mutations in the MCPH1 (microcephalin 1) gene, located at chromosome 8p23.1, result in two autosomal recessive disorders: primary microcephaly and premature chromosome condensation syndrome. MCPH1 has also been shown to be downregulated in breast, prostate and ovarian cancers, and mutated in 1/10 br...

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Detalles Bibliográficos
Autores principales: Venkatesh, Thejaswini, Nagashri, Mathighatta Nagaraj, Swamy, Shivananda S., Mohiyuddin, S. M. Azeem, Gopinath, Kodaganur S., Kumar, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589425/
https://www.ncbi.nlm.nih.gov/pubmed/23472065
http://dx.doi.org/10.1371/journal.pone.0054643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589425/
https://www.ncbi.nlm.nih.gov/pubmed/23472065
http://dx.doi.org/10.1371/journal.pone.0054643

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