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Role of the Functional Toll-Like Receptor-9 Promoter Polymorphism (-1237T/C) in Increased Risk of End-Stage Renal Disease: A Case-Control Study
Inflammation induced by infectious and noninfectious triggers in the kidney may lead to end stage renal disease (ESRD). Toll-like receptor 9 (TLR-9) a receptor for CpG DNA is involved in activation of immune cells in renal disease and may contribute to chronic inflammatory disease progression throug...
Autores principales: | Yang, Hsin-Yi, Lu, Kuo-Cheng, Lee, Herng-Sheng, Huang, Shih-Ming, Lin, Yuh-Feng, Wu, Chia-Chao, Salter, Donald M., Su, Sui-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589433/ https://www.ncbi.nlm.nih.gov/pubmed/23472199 http://dx.doi.org/10.1371/journal.pone.0058444 |
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