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Effects of Cyclic Intermittent Hypoxia on ET-1 Responsiveness and Endothelial Dysfunction of Pulmonary Arteries in Rats

Obstructive sleep apnoea (OSA) is a risk factor for cardiovascular disorders and in some cases is complication of pulmonary hypertension. We simulated OSA by exposing rats to cyclic intermittent hypoxia (CIH) to investigate its effect on pulmonary vascular endothelial dysfunction. Sprague-Dawley Rat...

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Detalles Bibliográficos
Autores principales:	Wang, Zhuo, Li, Ai-Ying, Guo, Qiu-Hong, Zhang, Jian-Ping, An, Qi, Guo, Ya-jing, Chu, Li, Weiss, J. Woodrow, Ji, En-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589442/ https://www.ncbi.nlm.nih.gov/pubmed/23555567 http://dx.doi.org/10.1371/journal.pone.0058078

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