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5′ UTR Control of Native ERG and of Tmprss2:ERG Variants Activity in Prostate Cancer
ERG, a member of the ETS transcription factor family, is frequently overexpressed in prostate cancer as a result of its fusion to the androgen-responsive Tmprss2 gene. Different genomic rearrangements and alternative splicing events around the junction region lead to multiple combination of Tmprss2:...
Autores principales: | Zammarchi, Francesca, Boutsalis, George, Cartegni, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589450/ https://www.ncbi.nlm.nih.gov/pubmed/23472063 http://dx.doi.org/10.1371/journal.pone.0049721 |
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