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Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Accumulating evidence(s) indicate that CXCL12-CXCR4 signaling cascade plays an important role in the process of invasion and metastasis that accounts for more than 80% of deaths in hepatocellular carcinoma (HCC) patients. Thus, identification of novel agents that can downregulate CXCR4 expression an...

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Detalles Bibliográficos
Autores principales:	Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Ong, Tina H., Subramaniam, Aruljothi, Siveen, Kodappully Sivaraman, Perumal, Ekambaram, Samy, Ramar Perumal, Bist, Pradeep, Lim, Lina H. K., Kumar, Alan Prem, Hui, Kam M., Sethi, Gautam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589458/ https://www.ncbi.nlm.nih.gov/pubmed/23472074 http://dx.doi.org/10.1371/journal.pone.0057015

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