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Activation of Akt by Advanced Glycation End Products (AGEs): Involvement of IGF-1 Receptor and Caveolin-1

Diabetes is characterized by chronic hyperglycemia, which in turn facilitates the formation of advanced glycation end products (AGEs). AGEs activate signaling proteins such as Src, Akt and ERK1/2. However, the mechanisms by which AGEs activate these kinases remain unclear. We examined the effect of...

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Detalles Bibliográficos
Autores principales:	Yang, Su-Jung, Chen, Chen-Yu, Chang, Geen-Dong, Wen, Hui-Chin, Chen, Ching-Yu, Chang, Shi-Chuan, Liao, Jyh-Fei, Chang, Chung-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589465/ https://www.ncbi.nlm.nih.gov/pubmed/23472139 http://dx.doi.org/10.1371/journal.pone.0058100

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