Strain Typing of Classical Scrapie by Transgenic Mouse Bioassay Using Protein Misfolding Cyclic Amplification to Replace Primary Passage

According to traditional murine bioassay methodology, prions must be serially passaged within a new host before a stable phenotype, and therefore a strain, can be assigned. Prions often transmit with difficulty from one species to another; a property termed the transmission barrier. Transgenic mouse...

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Detalles Bibliográficos
Autores principales: Beck, Katy E., Thorne, Leigh, Lockey, Richard, Vickery, Christopher M., Terry, Linda A., Bujdoso, Raymond, Spiropoulos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589467/
https://www.ncbi.nlm.nih.gov/pubmed/23472112
http://dx.doi.org/10.1371/journal.pone.0057851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589467/
https://www.ncbi.nlm.nih.gov/pubmed/23472112
http://dx.doi.org/10.1371/journal.pone.0057851

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