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Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations
Large-scale analysis of balanced chromosomal translocation breakpoints has shown nonhomologous end joining and microhomology-mediated repair to be the main drivers of interchromosomal structural aberrations. Breakpoint sequences of de novo unbalanced translocations have not yet been investigated sys...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589530/ https://www.ncbi.nlm.nih.gov/pubmed/23212949 http://dx.doi.org/10.1101/gr.145631.112 |