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iReckon: Simultaneous isoform discovery and abundance estimation from RNA-seq data

High-throughput RNA sequencing (RNA-seq) promises to revolutionize our understanding of genes and their role in human disease by characterizing the RNA content of tissues and cells. The realization of this promise, however, is conditional on the development of effective computational methods for the...

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Detalles Bibliográficos
Autores principales: Mezlini, Aziz M., Smith, Eric J.M., Fiume, Marc, Buske, Orion, Savich, Gleb L., Shah, Sohrab, Aparicio, Sam, Chiang, Derek Y., Goldenberg, Anna, Brudno, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589540/
https://www.ncbi.nlm.nih.gov/pubmed/23204306
http://dx.doi.org/10.1101/gr.142232.112