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Highly active zinc-finger nucleases by extended modular assembly
Zinc-finger nucleases (ZFNs) are important tools for genome engineering. Despite intense interest by many academic groups, the lack of robust noncommercial methods has hindered their widespread use. The modular assembly (MA) of ZFNs from publicly available one-finger archives provides a rapid method...
Autores principales: | Bhakta, Mital S., Henry, Isabelle M., Ousterout, David G., Das, Kumitaa Theva, Lockwood, Sarah H., Meckler, Joshua F., Wallen, Mark C., Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A., Segal, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589541/ https://www.ncbi.nlm.nih.gov/pubmed/23222846 http://dx.doi.org/10.1101/gr.143693.112 |
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