Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways

Improved methods for engineering sequence-specific nucleases, including zinc finger nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible to precisely modify plant genomes. However, the success of genome modification is largely dependent on the intrinsic activity of the enginee...

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Detalles Bibliográficos
Autores principales: Qi, Yiping, Zhang, Yong, Zhang, Feng, Baller, Joshua A., Cleland, Spencer C., Ryu, Yungil, Starker, Colby G., Voytas, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589543/
https://www.ncbi.nlm.nih.gov/pubmed/23282329
http://dx.doi.org/10.1101/gr.145557.112

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