CTX-M-55-Type Extended-Spectrum β-lactamase-Producing Shigella sonnei Isolated from a Korean Patient Who Had Travelled to China

We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3℃). S. sonnei was isolated from her stoo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Wonmok, Chung, Hae-Sun, Lee, Hyukmin, Yum, Jong Hwa, Yong, Dongeun, Jeong, Seok Hoon, Lee, Kyungwon, Chong, Yunsop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589641/
https://www.ncbi.nlm.nih.gov/pubmed/23483349
http://dx.doi.org/10.3343/alm.2013.33.2.141
Descripción
Sumario:We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3℃). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the bla(CTX-M-55) gene. The bla(CTX-M-55) gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the bla(CTX-M-55) gene was located on a plasmid of approximately 130 kb.

Ejemplares similares