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Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a Link?

Parkinson’s disease patients exhibit progressive spreading of aggregated α-synuclein in the nervous system. This slow process follows a specific pattern in an inflamed tissue environment. Recent research suggests that prion-like mechanisms contribute to the propagation of α-synuclein pathology. Litt...

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Detalles Bibliográficos
Autores principales:	Lema Tomé, Carla M., Tyson, Trevor, Rey, Nolwen L., Grathwohl, Stefan, Britschgi, Markus, Brundin, Patrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Humana Press Inc 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589652/ https://www.ncbi.nlm.nih.gov/pubmed/22544647 http://dx.doi.org/10.1007/s12035-012-8267-8

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