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Phase II trial of single-agent foretinib (GSK1363089) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
Background Foretinib is a small-molecule, oral multikinase inhibitor primarily targeting the mesenchymal epithelial transition (MET) factor receptor, and the vascular endothelial growth factor receptor 2. We conducted a phase II study to evaluate the single-agent activity and tolerability of foretin...
Autores principales: | Seiwert, Tanguy, Sarantopoulos, John, Kallender, Howard, McCallum, Stewart, Keer, Harold N., Blumenschein, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589657/ https://www.ncbi.nlm.nih.gov/pubmed/22918720 http://dx.doi.org/10.1007/s10637-012-9861-3 |
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