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Modeling Wnt/β-Catenin Target Gene Expression in APC and Wnt Gradients Under Wild Type and Mutant Conditions

The Wnt/β-catenin pathway is involved in the regulation of a multitude of physiological processes by controlling the differential expression of target genes. In certain tissues such as the adult liver, the Wnt/β-catenin pathway can attain different levels of activity due to gradients of Wnt ligands...

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Detalles Bibliográficos
Autores principales: Benary, Uwe, Kofahl, Bente, Hecht, Andreas, Wolf, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589749/
https://www.ncbi.nlm.nih.gov/pubmed/23508686
http://dx.doi.org/10.3389/fphys.2013.00021

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