Influenza Virus-like Particle Containing Two Different Subtypes of Hemagglutinin Confers Protection in Mice Against Lethal Challenge With A/PR8 (H1N1) and A/HK (H3N2) Viruses

BACKGROUND: Preventing the seasonal or pandemic outbreak of influenza can be powerful and cost-effective. OBJECTIVES: In this study, we constructed a novel virus-like particle (VLP) platform that contains two hemagglutinin (HA) subtypes and evaluated immunogenicity of constructed VLP in mice. MATERI...

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Detalles Bibliográficos
Autores principales: Rezaei, Farhad, Mirshafiey, Abbas, Shahmahmoodi, Shohreh, Shoja, Zabihollah, Ghavami, Nastaran, Mokhtari-Azad, Talat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589784/
https://www.ncbi.nlm.nih.gov/pubmed/23487492
http://dx.doi.org/10.5812/ircmj.6252

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