Choices in kidney transplantation in type 1 diabetes: Are there skeletal benefits of the endocrine pancreas?

Traditionally, recipients of a simultaneous pancreas-kidney (SPK) versus kidney transplant alone (KTA) were thought to have higher fracture risk. Using a large US registry, Nikkel et al observed lower rates of fracture hospitalization among patients with type 1 diabetes after SPK compared to KTA, pa...

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Detalles Bibliográficos
Autor principal: Scialla, Julia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589985/
https://www.ncbi.nlm.nih.gov/pubmed/23446255
http://dx.doi.org/10.1038/ki.2012.438
Descripción
Sumario:Traditionally, recipients of a simultaneous pancreas-kidney (SPK) versus kidney transplant alone (KTA) were thought to have higher fracture risk. Using a large US registry, Nikkel et al observed lower rates of fracture hospitalization among patients with type 1 diabetes after SPK compared to KTA, particularly among men. It is not known whether the apparent benefit of SPK is due to improved bone strength or fewer falls, but these findings may influence transplant decision making.

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