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WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells

Wnt5a is a non-canonical signaling Wnt. Low expression of WNT5A is correlated with poor prognosis in breast cancer patients. The highly invasive breast cancer cell lines, MDA-MB-231 and 4T1, express very low levels of WNT5A. To determine if enhanced expression of WNT5A would affect metastatic behavi...

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Detalles Bibliográficos
Autores principales: Jiang, Wen, Crossman, David K., Mitchell, Elizabeth H., Sohn, Philip, Crowley, Michael R., Serra, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590134/
https://www.ncbi.nlm.nih.gov/pubmed/23484019
http://dx.doi.org/10.1371/journal.pone.0058329