Cargando…
WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells
Wnt5a is a non-canonical signaling Wnt. Low expression of WNT5A is correlated with poor prognosis in breast cancer patients. The highly invasive breast cancer cell lines, MDA-MB-231 and 4T1, express very low levels of WNT5A. To determine if enhanced expression of WNT5A would affect metastatic behavi...
Autores principales: | Jiang, Wen, Crossman, David K., Mitchell, Elizabeth H., Sohn, Philip, Crowley, Michael R., Serra, Rosa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590134/ https://www.ncbi.nlm.nih.gov/pubmed/23484019 http://dx.doi.org/10.1371/journal.pone.0058329 |
Ejemplares similares
-
Aberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast Cancer
por: Inoue, Kazushi, et al.
Publicado: (2015) -
CD44 increases the efficiency of distant metastasis of breast cancer
por: McFarlane, Suzanne, et al.
Publicado: (2015) -
CD44V3, an Alternatively Spliced Form of CD44, Promotes Pancreatic Cancer Progression
por: Zhu, Hanzhang, et al.
Publicado: (2022) -
CD44 splice isoform switching determines breast cancer stem cell state
por: Zhang, Honghong, et al.
Publicado: (2019) -
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis
por: Liu, Bowen, et al.
Publicado: (2023)