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Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease

Graft-versus-host disease (GvHD) is a key contributor to the morbidity and mortality after allogeneic hematopoetic stem cell transplantation (HSCT). Regulatory Foxp3(+) CD4(+) T cells (T(reg)) suppress conventional T cell activation and can control GvHD. In our previous work, we demonstrate that a b...

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Detalles Bibliográficos
Autores principales:	Weber, Michael, Lupp, Corinna, Stein, Pamela, Kreft, Andreas, Bopp, Tobias, Wehler, Thomas C., Schmitt, Edgar, Schild, Hansjörg, Radsak, Markus P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590136/ https://www.ncbi.nlm.nih.gov/pubmed/23483980 http://dx.doi.org/10.1371/journal.pone.0058110

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