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The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways
Tumstatin is an anti-angiogenic collagen IV α3 fragment, levels of which are reduced in the airways of asthmatics. Its reduction may be due to the degradation by extracellular matrix (ECM) proteases. Cathepsins play a role in ECM remodelling, with cathepsin D, H and K (CTSD, CTSH and CTSK) being ass...
Autores principales: | Faiz, Alen, Tjin, Gavin, Harkness, Louise, Weckmann, Markus, Bao, Shisan, Black, Judith L., Oliver, Brian G. G., Burgess, Janette K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590183/ https://www.ncbi.nlm.nih.gov/pubmed/23483898 http://dx.doi.org/10.1371/journal.pone.0057245 |
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