Small Hydrophobic Protein of Human Metapneumovirus Does Not Affect Virus Replication and Host Gene Expression In Vitro

Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compared with wild type HMPV in several cell-lines. In a...

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Detalles Bibliográficos
Autores principales: de Graaf, Miranda, Herfst, Sander, Aarbiou, Jamil, Burgers, Peter C., Zaaraoui-Boutahar, Fatiha, Bijl, Maarten, van IJcken, Wilfred, Schrauwen, Eefje J. A., Osterhaus, Albert D. M. E., Luider, Theo M., Scholte, Bob J., Fouchier, Ron A. M., Andeweg, Arno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590193/
https://www.ncbi.nlm.nih.gov/pubmed/23484037
http://dx.doi.org/10.1371/journal.pone.0058572

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