Cargando…
Essential Roles of the Kar2/BiP Molecular Chaperone Downstream of the UPR Pathway in Cryptococcus neoformans
The endoplasmic reticulum (ER) is a central hub where secreted or membrane-bound proteins are maturated and folded properly in eukaryotes. Maintenance of ER homeostasis is particularly important for human fungal pathogens, such as Cryptococcus neoformans, which encounter a plethora of host-mediated...
Autores principales: | Jung, Kwang-Woo, Kang, Hyun Ah, Bahn, Yong-Sun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590199/ https://www.ncbi.nlm.nih.gov/pubmed/23484059 http://dx.doi.org/10.1371/journal.pone.0058956 |
Ejemplares similares
-
Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans
por: Cheon, Seon Ah, et al.
Publicado: (2011) -
BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast
Publicado: (1995) -
Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans
por: Jung, Kwang-Woo, et al.
Publicado: (2022) -
UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
por: Kopp, Megan C, et al.
Publicado: (2019) -
Endoplasmic reticulum stress regulation of the Kar2p/BiP chaperone alleviates proteotoxicity via dual degradation pathways
por: Hsu, Chia-Ling, et al.
Publicado: (2012)