IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative, proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial effects of IFNB1 in experimental breast cancers, clinical translation has been disappointing, possibly due to induction of surv...

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Detalles Bibliográficos
Autores principales: Ambjørn, Malene, Ejlerskov, Patrick, Liu, Yawei, Lees, Michael, Jäättelä, Marja, Issazadeh-Navikas, Shohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590251/
https://www.ncbi.nlm.nih.gov/pubmed/23221969
http://dx.doi.org/10.4161/auto.22831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590251/
https://www.ncbi.nlm.nih.gov/pubmed/23221969
http://dx.doi.org/10.4161/auto.22831

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