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IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function
IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative, proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial effects of IFNB1 in experimental breast cancers, clinical translation has been disappointing, possibly due to induction of surv...
Autores principales: | Ambjørn, Malene, Ejlerskov, Patrick, Liu, Yawei, Lees, Michael, Jäättelä, Marja, Issazadeh-Navikas, Shohreh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590251/ https://www.ncbi.nlm.nih.gov/pubmed/23221969 http://dx.doi.org/10.4161/auto.22831 |
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