Parental Imbalances Involving Chromosomes 15q and 22q May Predispose to the Formation of De Novo Pathogenic Microdeletions and Microduplications in the Offspring

Microarray-based comparative genomic hybridization (array-CGH) led to the discovery of genetic abnormalities among patients with complex phenotype and normal karyotype. Also several apparently normal individuals have been found to be carriers of cryptic imbalances, hence the importance to perform pa...

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Detalles Bibliográficos
Autores principales: Capra, Valeria, Mascelli, Samantha, Garrè, Maria Luisa, Nozza, Paolo, Vaccari, Carlotta, Bricco, Lara, Sloan-Béna, Frédérique, Gimelli, Stefania, Cuoco, Cristina, Gimelli, Giorgio, Tassano, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590287/
https://www.ncbi.nlm.nih.gov/pubmed/23483941
http://dx.doi.org/10.1371/journal.pone.0057910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590287/
https://www.ncbi.nlm.nih.gov/pubmed/23483941
http://dx.doi.org/10.1371/journal.pone.0057910

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