Low background and high contrast PET imaging of amyloid-β with [(11)C]AZD2995 and [(11)C]AZD2184 in Alzheimer’s disease patients

PURPOSE: The aim of this study was to evaluate AZD2995 side by side with AZD2184 as novel PET radioligands for imaging of amyloid-β in Alzheimer’s disease (AD). METHODS: In vitro binding of tritium-labelled AZD2995 and AZD2184 was studied and compared with that of the established amyloid-β PET radio...

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Detalles Bibliográficos
Autores principales: Forsberg, Anton, Juréus, Anders, Cselényi, Zsolt, Eriksdotter, Maria, Freund-Levi, Yvonne, Jeppsson, Fredrik, Swahn, Britt-Marie, Sandell, Johan, Julin, Per, Schou, Magnus, Andersson, Jan, Johnström, Peter, Varnäs, Katarina, Halldin, Christer, Farde, Lars, Svensson, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590405/
https://www.ncbi.nlm.nih.gov/pubmed/23324871
http://dx.doi.org/10.1007/s00259-012-2322-6

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