ErbB2 Dephosphorylation and Anti-Proliferative Effects of Neuregulin-1 in ErbB2-Overexpressing Cells; Re-evaluation of Their Low-Affinity Interaction

Neuregulin-1 binds to ErbB3 and ErbB4 and regulates cancer proliferation and differentiation. Neuregulin-1 had been suggested to also react with ErbB2, but this argument becomes controversial. Here, we re-evaluated the cellular responses and ErbB2 interaction of neuregulin-1 in ErbB2 overexpressing...

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Detalles Bibliográficos
Autores principales: Wang, Ran, Iwakura, Yuriko, Araki, Kazuaki, Keino-Masu, Kazuko, Masu, Masayuki, Wang, Xue-yi, Takei, Nobuyuki, Higashiyama, Shigeki, Nawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590560/
https://www.ncbi.nlm.nih.gov/pubmed/23466678
http://dx.doi.org/10.1038/srep01402

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