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Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites

Gold nanoparticles (GNPs) and GNP-based multifunctional nanocomposites are the subject of intensive studies and biomedical applications. This minireview summarizes our recent efforts in analytical and theranostic applications of engineered GNPs and nanocomposites by using plasmonic properties of GNP...

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Detalles Bibliográficos
Autores principales: Khlebtsov, Nikolai, Bogatyrev, Vladimir, Dykman, Lev, Khlebtsov, Boris, Staroverov, Sergey, Shirokov, Alexander, Matora, Larisa, Khanadeev, Vitaly, Pylaev, Timofey, Tsyganova, Natalia, Terentyuk, Georgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590586/
https://www.ncbi.nlm.nih.gov/pubmed/23471188
http://dx.doi.org/10.7150/thno.5716
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author Khlebtsov, Nikolai
Bogatyrev, Vladimir
Dykman, Lev
Khlebtsov, Boris
Staroverov, Sergey
Shirokov, Alexander
Matora, Larisa
Khanadeev, Vitaly
Pylaev, Timofey
Tsyganova, Natalia
Terentyuk, Georgy
author_facet Khlebtsov, Nikolai
Bogatyrev, Vladimir
Dykman, Lev
Khlebtsov, Boris
Staroverov, Sergey
Shirokov, Alexander
Matora, Larisa
Khanadeev, Vitaly
Pylaev, Timofey
Tsyganova, Natalia
Terentyuk, Georgy
author_sort Khlebtsov, Nikolai
collection PubMed
description Gold nanoparticles (GNPs) and GNP-based multifunctional nanocomposites are the subject of intensive studies and biomedical applications. This minireview summarizes our recent efforts in analytical and theranostic applications of engineered GNPs and nanocomposites by using plasmonic properties of GNPs and various optical techniques. Specifically, we consider analytical biosensing; visualization and bioimaging of bacterial, mammalian, and plant cells; photodynamic treatment of pathogenic bacteria; and photothermal therapy of xenografted tumors. In addition to recently published reports, we discuss new data on dot immunoassay diagnostics of mycobacteria, multiplexed immunoelectron microscopy analysis of Azospirillum brasilense, materno-embryonic transfer of GNPs in pregnant rats, and combined photodynamic and photothermal treatment of rat xenografted tumors with gold nanorods covered by a mesoporous silica shell doped with hematoporphyrin.
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spelling pubmed-35905862013-03-07 Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites Khlebtsov, Nikolai Bogatyrev, Vladimir Dykman, Lev Khlebtsov, Boris Staroverov, Sergey Shirokov, Alexander Matora, Larisa Khanadeev, Vitaly Pylaev, Timofey Tsyganova, Natalia Terentyuk, Georgy Theranostics Review Gold nanoparticles (GNPs) and GNP-based multifunctional nanocomposites are the subject of intensive studies and biomedical applications. This minireview summarizes our recent efforts in analytical and theranostic applications of engineered GNPs and nanocomposites by using plasmonic properties of GNPs and various optical techniques. Specifically, we consider analytical biosensing; visualization and bioimaging of bacterial, mammalian, and plant cells; photodynamic treatment of pathogenic bacteria; and photothermal therapy of xenografted tumors. In addition to recently published reports, we discuss new data on dot immunoassay diagnostics of mycobacteria, multiplexed immunoelectron microscopy analysis of Azospirillum brasilense, materno-embryonic transfer of GNPs in pregnant rats, and combined photodynamic and photothermal treatment of rat xenografted tumors with gold nanorods covered by a mesoporous silica shell doped with hematoporphyrin. Ivyspring International Publisher 2013-02-20 /pmc/articles/PMC3590586/ /pubmed/23471188 http://dx.doi.org/10.7150/thno.5716 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Review
Khlebtsov, Nikolai
Bogatyrev, Vladimir
Dykman, Lev
Khlebtsov, Boris
Staroverov, Sergey
Shirokov, Alexander
Matora, Larisa
Khanadeev, Vitaly
Pylaev, Timofey
Tsyganova, Natalia
Terentyuk, Georgy
Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title_full Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title_fullStr Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title_full_unstemmed Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title_short Analytical and Theranostic Applications of Gold Nanoparticles and Multifunctional Nanocomposites
title_sort analytical and theranostic applications of gold nanoparticles and multifunctional nanocomposites
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590586/
https://www.ncbi.nlm.nih.gov/pubmed/23471188
http://dx.doi.org/10.7150/thno.5716
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