Cargando…

Inflammatory Stress Exacerbates the Progression of Cardiac Fibrosis in High-Fat-Fed Apolipoprotein E Knockout Mice via Endothelial-Mesenchymal Transition

Background Chronic inflammation plays a crucial role in the progression of cardiac fibrosis. This study investigated whether inflammation exacerbated the progression of cardiac fibrosis in high-fat-fed apolipoprotein E knockout (ApoE KO) mice via endothelial-mesenchymal transition (EndMT). Methods T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Kun Ling, Liu, Jing, Ni, Jie, Zhang, Yang, Lv, Lin Li, Tang, Ri Ning, Ni, Hai Feng, Ruan, Xiong Zhong, Liu, Bi Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590602/ https://www.ncbi.nlm.nih.gov/pubmed/23471419 http://dx.doi.org/10.7150/ijms.5723

Ejemplares similares

Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells
por: Ni, Jie, et al.
Publicado: (2013)

MicroRNA-126 inhibits endothelial permeability and apoptosis in apolipoprotein E-knockout mice fed a high-fat diet
por: Cheng, Xiao-Wen, et al.
Publicado: (2017)

SIRT2 knockout exacerbates insulin resistance in high fat-fed mice
por: Lantier, Louise, et al.
Publicado: (2018)

The Fat-Fed Apolipoprotein E Knockout Mouse Brachiocephalic Artery in the Study of Atherosclerotic Plaque Rupture
por: Bond, Andrew R., et al.
Publicado: (2011)

Increased mTORC1 activity contributes to atherosclerosis in apolipoprotein E knockout mice and in vascular smooth muscle cells()
por: Ma, Kun Ling, et al.
Publicado: (2013)

Apple Supplementation Improves Hemodynamic Parameter and Attenuates Atherosclerosis in High-Fat Diet-Fed Apolipoprotein E-Knockout Mice
por: Soleti, Raffaella, et al.
Publicado: (2020)

Folate Deficiency Enhanced Inflammation and Exacerbated Renal Fibrosis in High-Fat High-Fructose Diet-Fed Mice
por: Chan, Chun-Wai, et al.
Publicado: (2023)

Sildenafil restores endothelial function in the apolipoprotein E knockout mouse
por: Balarini, Camille M, et al.
Publicado: (2013)

Reduced Atherosclerotic Lesion Size in P-Selectin Deficient Apolipoprotein E-Knockout Mice Fed a Chow but Not a Fat Diet
por: Bourdillon, Marie-Claude, et al.
Publicado: (2006)

Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis
por: Singh, Shweta, et al.
Publicado: (2020)

Green tea polyphenol treatment attenuates atherosclerosis in high-fat diet-fed apolipoprotein E-knockout mice via alleviating dyslipidemia and up-regulating autophagy
por: Ding, Shibin, et al.
Publicado: (2017)

Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy
por: Zhang, Lu, et al.
Publicado: (2021)

Monobutyrin and monovalerin improve gut–blood–brain biomarkers and alter gut microbiota composition in high-fat fed apolipoprotein-E-knockout rats
por: Nguyen, Thao Duy, et al.
Publicado: (2022)

Activation of 5-HT(2) Receptors Reduces Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice
por: Flanagan, Thomas W., et al.
Publicado: (2019)

Angiotensin Receptor Blocker and Neprilysin Inhibitor Suppresses Cardiac Dysfunction by Accelerating Myocardial Angiogenesis in Apolipoprotein E-Knockout Mice Fed a High-Fat Diet
por: Suematsu, Yasunori, et al.
Publicado: (2021)

Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR(−/−) mice fed on high-fat diet
por: Liu, Lin, et al.
Publicado: (2019)

Rosiglitazone modulates collagen deposition and metabolism in atherosclerotic plaques of fat-fed ApoE-knockout mice
por: ZHOU, MINGXUE, et al.
Publicado: (2015)

Hypothyroidism Exacerbates Thrombophilia in Female Rats Fed with a High Fat Diet
por: Mangge, Harald, et al.
Publicado: (2015)

Author Correction: Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR(−/−) mice fed on high-fat diet
por: Liu, Lin, et al.
Publicado: (2020)

Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice
por: Yang, Qiuhua, et al.
Publicado: (2021)

Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet
por: Cui, Yingjie, et al.
Publicado: (2017)

Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice
por: Liu, Xiao Ling, et al.
Publicado: (2012)

Atherosclerosis affects calcium signalling in endothelial cells from apolipoprotein E knockout mice before plaque formation
por: Prendergast, Clodagh, et al.
Publicado: (2014)

Combinatorial interference of toll-like receptor 2 and 4 synergistically stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice
por: Yang, Jian Min, et al.
Publicado: (2011)

Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia
por: Yao, Yufeng, et al.
Publicado: (2018)

Dietary Cholic Acid Exacerbates Liver Fibrosis in NASH Model of Sprague–Dawley Rats Fed a High-Fat and High-Cholesterol Diet
por: Ichimura-Shimizu, Mayuko, et al.
Publicado: (2022)

2-Hydroxypropyl-beta-cyclodextrin Treatment Does Not Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice
por: Snip, Olga S.C., et al.
Publicado: (2022)

Endothelial to mesenchymal transition contributes to arsenic-trioxide-induced cardiac fibrosis
por: Zhang, Yong, et al.
Publicado: (2016)

Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis
por: Liu, Tianju, et al.
Publicado: (2015)

Age-Related Changes in the Behavior of Apolipoprotein E Knockout Mice
por: Fuentes, Dasha, et al.
Publicado: (2018)

Apolipoprotein E knockout rabbit model of intracranial atherosclerotic disease
por: Zabriskie, Matthew S., et al.
Publicado: (2020)

Capillarized Liver Sinusoidal Endothelial Cells Undergo Partial Endothelial-Mesenchymal Transition to Actively Deposit Sinusoidal ECM in Liver Fibrosis
por: Ruan, Bai, et al.
Publicado: (2021)

Endothelial Cell-Specific Molecule 1 Promotes Endothelial to Mesenchymal Transition in Renal Fibrosis
por: Hung, Tung-Wei, et al.
Publicado: (2020)

Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial–Mesenchymal Transition
por: Zhang, Yanhong, et al.
Publicado: (2021)

CXCL2 Impairs Functions of Bone Marrow Mesenchymal Stem Cells and Can Serve as a Serum Marker in High-Fat Diet-Fed Rats
por: Bi, Jianhai, et al.
Publicado: (2021)

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice
por: Lebeau, Paul F., et al.
Publicado: (2019)

Atherosclerosis differentially affects calcium signalling in endothelial cells from aortic arch and thoracic aorta in Apolipoprotein E knockout mice
por: Prendergast, Clodagh, et al.
Publicado: (2014)

Hyperoside Nanomicelles Alleviate Atherosclerosis by Modulating the Lipid Profile and Intestinal Flora Structure in High-Fat-Diet-Fed Apolipoprotein-E-Deficient Mice
por: Shi, Yuwen, et al.
Publicado: (2023)

Periodontitis-induced systemic inflammation exacerbates atherosclerosis partly via endothelial–mesenchymal transition in mice
por: Suh, Jin Sook, et al.
Publicado: (2019)

The Influence of Trehalose on Atherosclerosis and Hepatic Steatosis in Apolipoprotein E Knockout Mice
por: Stachowicz, Aneta, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_prli1q9fps5cqe7an6eqg9mjs6