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Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer

BACKGROUND: The epithelial cell adhesion molecule (EpCAM) is overexpressed on most carcinomas. Dependent on the tumour type, its overexpression is either associated with improved or worse patient survival. For ovarian cancer, however, the role of EpCAM remains unclear. METHODS: Cell survival of ovar...

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Detalles Bibliográficos
Autores principales: van der Gun, B T F, Huisman, C, Stolzenburg, S, Kazemier, H G, Ruiters, M H J, Blancafort, P, Rots, M G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590680/
https://www.ncbi.nlm.nih.gov/pubmed/23403823
http://dx.doi.org/10.1038/bjc.2013.45