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A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data
Recent developments in RNA-sequencing (RNA-seq) technology have led to a rapid increase in gene expression data in the form of counts. RNA-seq can be used for a variety of applications, however, identifying differential expression (DE) remains a key task in functional genomics. There have been a num...
Autores principales: | Wu, Hao, Wang, Chi, Wu, Zhijin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590927/ https://www.ncbi.nlm.nih.gov/pubmed/23001152 http://dx.doi.org/10.1093/biostatistics/kxs033 |
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