Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient

F-18 FDG PET-CT scanning plays an important role in the management of fever of unknown origin (FUO). Some elderly patients with FUO can be in their terminal stage of life. An elderly woman was referred for a PET-CT scan to find the etiology of FUO. The scan was inconclusive but showed significantly...

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Detalles Bibliográficos
Autores principales: Sonoda, Luke I., Sanghera, Bal, Vivian, Gill, Wong, Wai Lup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590967/
https://www.ncbi.nlm.nih.gov/pubmed/23486726
http://dx.doi.org/10.4274/Mirt.136
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author Sonoda, Luke I.
Sanghera, Bal
Vivian, Gill
Wong, Wai Lup
author_facet Sonoda, Luke I.
Sanghera, Bal
Vivian, Gill
Wong, Wai Lup
author_sort Sonoda, Luke I.
collection PubMed
description F-18 FDG PET-CT scanning plays an important role in the management of fever of unknown origin (FUO). Some elderly patients with FUO can be in their terminal stage of life. An elderly woman was referred for a PET-CT scan to find the etiology of FUO. The scan was inconclusive but showed significantly reduced FDG uptake in the brain and heart, despite normal physiological uptake in the liver and bowel. The patient deceased within the hour post scan. Contrary to common belief, we have shown that cerebral glucose metabolism via cerebral perfusion may be compromised before hepatic and bowel perfusion in a dying patient. Conflict of interest:None declared.
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spelling pubmed-35909672013-03-13 Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient Sonoda, Luke I. Sanghera, Bal Vivian, Gill Wong, Wai Lup Mol Imaging Radionucl Ther Case Report F-18 FDG PET-CT scanning plays an important role in the management of fever of unknown origin (FUO). Some elderly patients with FUO can be in their terminal stage of life. An elderly woman was referred for a PET-CT scan to find the etiology of FUO. The scan was inconclusive but showed significantly reduced FDG uptake in the brain and heart, despite normal physiological uptake in the liver and bowel. The patient deceased within the hour post scan. Contrary to common belief, we have shown that cerebral glucose metabolism via cerebral perfusion may be compromised before hepatic and bowel perfusion in a dying patient. Conflict of interest:None declared. Galenos Publishing 2012-08 2012-08-01 /pmc/articles/PMC3590967/ /pubmed/23486726 http://dx.doi.org/10.4274/Mirt.136 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sonoda, Luke I.
Sanghera, Bal
Vivian, Gill
Wong, Wai Lup
Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title_full Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title_fullStr Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title_full_unstemmed Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title_short Unexpected Significantly Reduced FDG Uptake in the Cerebrum Compared Against Normal Liver Uptake in a Dying Patient
title_sort unexpected significantly reduced fdg uptake in the cerebrum compared against normal liver uptake in a dying patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590967/
https://www.ncbi.nlm.nih.gov/pubmed/23486726
http://dx.doi.org/10.4274/Mirt.136
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