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p55PIK Transcriptionally Activated by MZF1 Promotes Colorectal Cancer Cell Proliferation

p55PIK, regulatory subunit of class IA phosphatidylinositol 3-kinase (PI3K), plays a crucial role in cell cycle progression by interaction with tumor repressor retinoblastoma (Rb) protein. A recent study showed that Rb protein can localize to the mitochondria in proliferative cells. Aberrant p55PIK...

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Detalles Bibliográficos
Autores principales: Deng, Yu, Wang, Jing, Wang, Guihua, Jin, Yuan, Luo, Xuelai, Xia, Xianmin, Gong, Jianping, Hu, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591147/
https://www.ncbi.nlm.nih.gov/pubmed/23509792
http://dx.doi.org/10.1155/2013/868131

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