An Inherited Heteroplasmic Mutation in Mitochondrial Gene COI in a Patient with Prostate Cancer Alters Reactive Oxygen, Reactive Nitrogen and Proliferation

Mitochondrial DNA (mtDNA) mutations have been found in many cancers but the physiological derangements caused by such mutations have remained elusive. Prostate cancer is associated with both inherited and somatic mutations in the cytochrome c oxidase (COI) gene. We present a prostate cancer patient-...

Descripción completa

Detalles Bibliográficos
Autores principales: Arnold, Rebecca S., Sun, Qian, Sun, Carrie Q., Richards, Jendai C., O'Hearn, Sean, Osunkoya, Adeboye O., Wallace, Douglas C., Petros, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591245/
https://www.ncbi.nlm.nih.gov/pubmed/23509693
http://dx.doi.org/10.1155/2013/239257

Ejemplares similares

Ejemplares similares