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Measurements of the Impact of 3′ End Sequences on Gene Expression Reveal Wide Range and Sequence Dependent Effects

A full understanding of gene regulation requires an understanding of the contributions that the various regulatory regions have on gene expression. Although it is well established that sequences downstream of the main promoter can affect expression, our understanding of the scale of this effect and...

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Detalles Bibliográficos
Autores principales: Shalem, Ophir, Carey, Lucas, Zeevi, Danny, Sharon, Eilon, Keren, Leeat, Weinberger, Adina, Dahan, Orna, Pilpel, Yitzhak, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591272/
https://www.ncbi.nlm.nih.gov/pubmed/23505350
http://dx.doi.org/10.1371/journal.pcbi.1002934