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Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?

Epigenetics may play a role in the pathophysiology of type 2 diabetes (T2D), and increased DNA methylation of the metabolic master regulator peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) has been reported in muscle and pancreatic islets from T2D patients and in musc...

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Detalles Bibliográficos
Autores principales:	Gillberg, Linn, Jacobsen, Stine, Ribel-Madsen, Rasmus, Gjesing, Anette Prior, Boesgaard, Trine W., Ling, Charlotte, Pedersen, Oluf, Hansen, Torben, Vaag, Allan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591301/ https://www.ncbi.nlm.nih.gov/pubmed/23505498 http://dx.doi.org/10.1371/journal.pone.0058384

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