Deoxyhypusine Hydroxylase from Plasmodium vivax, the Neglected Human Malaria Parasite: Molecular Cloning, Expression and Specific Inhibition by the 5-LOX Inhibitor Zileuton

Primaquine, an 8-aminoquinoline, is the only drug which cures the dormant hypnozoites of persistent liver stages from P. vivax. Increasing resistance needs the discovery of alternative pathways as drug targets to develop novel drug entities. Deoxyhypusine hydroxylase (DOHH) completes hypusine biosyn...

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Detalles Bibliográficos
Autores principales: Atemnkeng, Veronika Anyigoh, Pink, Mario, Schmitz-Spanke, Simone, Wu, Xian-Jun, Dong, Liang-Liang, Zhao, Kai-Hong, May, Caroline, Laufer, Stefan, Langer, Barbara, Kaiser, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591309/
https://www.ncbi.nlm.nih.gov/pubmed/23505486
http://dx.doi.org/10.1371/journal.pone.0058318

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