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α-Lipoic Acid Reduces Infarct Size and Preserves Cardiac Function in Rat Myocardial Ischemia/Reperfusion Injury through Activation of PI3K/Akt/Nrf2 Pathway

BACKGROUND: The present study investigates the effects and mechanisms of α-Lipoic acid (LA) on myocardial infarct size, cardiac function and cardiomyocyte apoptosis in rat hearts subjected to in vivo myocardial ischemia/reperfusion (MI/R) injury. METHODOLOGY/PRINCIPAL FINDINGS: Male adult rats under...

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Detalles Bibliográficos
Autores principales:	Deng, Chao, Sun, Zhongchan, Tong, Guang, Yi, Wei, Ma, Li, Zhao, Bijun, Cheng, Liang, Zhang, Jinzhou, Cao, Feng, Yi, Dinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591314/ https://www.ncbi.nlm.nih.gov/pubmed/23505496 http://dx.doi.org/10.1371/journal.pone.0058371

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