A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET

Ion channels and ion fluxes control many aspects of tissue homeostasis. During oncogenic transformation, critical ion channel functions may be perturbed but conserved tumor specific ion fluxes remain to be defined. Here we used the tumoricidal protein-lipid complex HAMLET as a probe to identify ion...

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Detalles Bibliográficos
Autores principales: Storm, Petter, Kjaer Klausen, Thomas, Trulsson, Maria, Ho CS, James, Dosnon, Marion, Westergren, Tomas, Chao, Yinxia, Rydström, Anna, Yang, Henry, Pedersen, Stine Falsig, Svanborg, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591364/
https://www.ncbi.nlm.nih.gov/pubmed/23505537
http://dx.doi.org/10.1371/journal.pone.0058578

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