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SIRT1 Polymorphism, Long-Term Survival and Glucose Tolerance in the General Population
Mutations that increase activity of Sir2 (silent information regulator 2) are associated with extended lifespan of yeast, fruit flies and worms. SIRT1, the human homolog of Sir2, that controls numerous physiological processes including the glucose metabolism, is considered a candidate gene for predi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591365/ https://www.ncbi.nlm.nih.gov/pubmed/23505545 http://dx.doi.org/10.1371/journal.pone.0058636 |