MUC1* Ligand, NM23-H1, Is a Novel Growth Factor That Maintains Human Stem Cells in a More Naïve State

We report that a single growth factor, NM23-H1, enables serial passaging of both human ES and iPS cells in the absence of feeder cells, their conditioned media or bFGF in a fully defined xeno-free media on a novel defined, xeno-free surface. Stem cells cultured in this system show a gene expression...

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Detalles Bibliográficos
Autores principales: Smagghe, Benoit J., Stewart, Andrew K., Carter, Mark G., Shelton, Laura M., Bernier, Kyle J., Hartman, Eric J., Calhoun, Amy K., Hatziioannou, Vasilios M., Lillacci, Gabriele, Kirk, Brian A., DiNardo, Brian A., Kosik, Kenneth S., Bamdad, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591366/
https://www.ncbi.nlm.nih.gov/pubmed/23505541
http://dx.doi.org/10.1371/journal.pone.0058601

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