Predicting where Small Molecules Bind at Protein-Protein Interfaces

Small molecules that bind at protein-protein interfaces may either block or stabilize protein-protein interactions in cells. Thus, some of these binding interfaces may turn into prospective targets for drug design. Here, we collected 175 pairs of protein-protein (PP) complexes and protein-ligand (PL...

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Detalles Bibliográficos
Autores principales: Walter, Peter, Metzger, Jennifer, Thiel, Christoph, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591369/
https://www.ncbi.nlm.nih.gov/pubmed/23505538
http://dx.doi.org/10.1371/journal.pone.0058583

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