Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients

BACKGROUND: The Cub and Sushi Multiple Domains 1 (CSMD1) gene, located on the short arm of chromosome 8, codes for a type I transmembrane protein whose function is currently unknown. CSMD1 expression is frequently lost in many epithelial cancers. Our goal was to characterize the relationships betwee...

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Detalles Bibliográficos
Autores principales: Shull, Austin Y., Clendenning, Megan L., Ghoshal-Gupta, Sampa, Farrell, Christopher L., Vangapandu, Hima V., Dudas, Larry, Wilkerson, Brent J., Buckhaults, Phillip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591376/
https://www.ncbi.nlm.nih.gov/pubmed/23505554
http://dx.doi.org/10.1371/journal.pone.0058731

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