Enhanced Aβ(1–40) Production in Endothelial Cells Stimulated with Fibrillar Aβ(1–42)

Amyloid accumulation in the brain of Alzheimer’s patients results from altered processing of the 39- to 43-amino acid amyloid β protein (Aβ). The mechanisms for the elevated amyloid (Aβ(1–42)) are considered to be over-expression of the amyloid precursor protein (APP), enhanced cleavage of APP to Aβ...

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Detalles Bibliográficos
Autores principales: Rajadas, Jayakumar, Sun, Wenchao, Li, Hai, Inayathullah, Mohammed, Cereghetti, Damiano, Tan, Aaron, de Mello Coelho, Valeria, Chrest, Francis J., Kusiak, John W., Smith, Wanli Wei, Taub, Dennis, Wu, Joseph C., Rifkind, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591408/
https://www.ncbi.nlm.nih.gov/pubmed/23505467
http://dx.doi.org/10.1371/journal.pone.0058194

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