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Suppressed cellular oscillations in after-hours mutant mice are associated with enhanced circadian phase-resetting
Within the core molecular clock, protein phosphorylation and degradation play a vital role in determining circadian period. The ‘after-hours’ (Afh) mutation in mouse slows the degradation of the core clock protein Cryptochrome, lengthening the period of the molecular clock in the suprachiasmatic nuc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Science Inc
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591715/ https://www.ncbi.nlm.nih.gov/pubmed/23207594 http://dx.doi.org/10.1113/jphysiol.2012.242198 |